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GE Healthcare y Affibody colaboran para desarrollar trazadores para la TEP

By Medimaging en español staff writers
02 Oct 2019

Imagen: La colaboración entre GE Healthcare y Affibody busca mejorar el tratamiento de pacientes con cáncer en todo el mundo (Fotografía cortesía de Shutterstock).GE Healthcare (Chicago, IL, EUA) y Affibody AB (Solna, Suecia) formaron una colaboración estratégica para desarrollar y comercializar trazadores para TEP basados en los de Affibody, con un enfoque inicial en HER2 y PD-L1.

Affibody es una compañía biofarmacéutica, en etapa clínica, centrada en el desarrollo de biofarmacéuticos innovadores bi y multiespecíficos de próxima generación, con base en sus plataformas de tecnología patentadas únicas: las moléculas de Affibody y Albumod. Affibody opera un modelo de medicina experimental enfocado y actualmente tiene tres programas en etapa clínica. Los dos primeros son programas terapéuticos dirigidos a la psoriasis y las enfermedades autoinmunes impulsadas por la células B, respectivamente. El tercero es un programa de diagnóstico por imagenología dirigido principalmente al cáncer de mama metastásico.

La tecnología Affibody es adecuada especialmente para el desarrollo de trazadores para la imagenología TEP y ABY-025, un trazador para la TEP basado en Affibody que detecta HER2, se encuentra actualmente en desarrollo clínico. ABY-025 proporciona un enfoque novedoso, no invasivo y rentable, para diagnosticar la expresión global de HER2 en pacientes con cáncer de mama metastásico mediante imágenes TEP. Affibody trabaja actualmente junto con instituciones académicas para explorar más la utilidad clínica de ABY-025. Está en desarrollo la molécula Affibody de unión a PD-L1 como una herramienta de diagnóstico para mejorar la selección y el seguimiento de pacientes con tratamientos inmuno-oncológicos. La colaboración con GE Healthcare acelerará los estudios a través de una etapa de prueba de concepto clínica.

“El inicio de una colaboración estratégica con GE Healthcare en torno a los trazadores para la TEP refleja el compromiso de Affibody con la medicina de precisión y el tratamiento guiado por biomarcadores para los pacientes. También subraya la competitividad de nuestra tecnología y el valor de los datos clínicos que se han generado con los agentes de imagenología basados en Affibody”, dijo David Bejker, director ejecutivo de Affibody. “Creemos que nuestra colaboración con GE Healthcare para desarrollar y comercializar estos agentes de imagenología hará una contribución significativa para mejorar el tratamiento de pacientes con cáncer a nivel mundial”.

“Reconocemos que la TEP juega un papel vital en el desarrollo y uso de inmunoterapias contra el cáncer, ya que es una forma no invasiva de medir la respuesta del paciente antes, durante y después del tratamiento”, dijo Sanka Thiru, Jefe de Oncología de Imagenología Molecular, en el negocio de Diagnóstico Farmacéutico de GE Healthcare. “Nos asociamos con empresas como Affibody para crear un portafolio de agentes de imagenología molecular para oncología, centrándonos en esos biomarcadores de enfermedades que ayudarán a acelerar el desarrollo de la próxima generación de tratamientos contra el cáncer”.

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GE Healthcare

GE Healthcare provides medical imaging and information technologies, medical diagnostics, patient monitoring systems, drug discovery, biopharmaceutical manufacturing technologies, performance improvement and performance solutions services. The company’s product areas include anesthesia delivery, diagnostic ECG, mammography, radiography, surgical imaging, maternal-infant care and clinical consumables.
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