The Fecal Occult Blood (FOB) One Step Assay is a rapid chromatographic immunoassay (non-invasive assay) for the qualitative detection of human hemoglobin in human feces specimens to screen for gastrointestinal bleeding, which may be an indicator of colorectal cancer, gastric cancer or peptic ulcers. Colorectal cancer occurs in the colon or rectum and is the third most common cancer for both men and women. Blood in the stool may be the only symptom of colorectal cancer. Other conditions that can cause blood in the stool include Hemorrhoids, Anal fissures, Colon polyps, Peptic ulcers, Ulcerative colitis, Gastroesophageal reflux disease (GERD), Crohn’s disease, use of aspirin or non-steroidal anti-inflammatory drugs (NSAIDs).