The cobas b 123 POC system is a fully automated POC system for in vitro measurement of pH, blood gases (BG), electrolytes (ISE), hematocrit (Hct), metabolites (Glu, Lac), total hemoglobin (tHb), hemoglobin derivatives (O2Hb, HHb, COHb, MetHb), oxygen saturation (SO2) and neonatal bilirubin (Bili). The mobile, cartridge-based, critical care blood gas and electrolytes analyzer is designed for POC blood gas testing with flexible configurations and a throughput of up to 30 samples per hour. It can be easily be customized to the clinical needs of the ICU, ER, NICU, OR, dialysis units or the laboratory.