EUROIMMUN AG

COVID-19 Immune Response Test
Quan-T-Cell

The Quan-T-Cell is an interferon-gamma (IFN-γ) release assay (IGRA) for the quantitative determination of the IFN-γ release by SARS-CoV-2-specific T cells. It supports the detection of a past pathogen contact with SARS-CoV-2 or the detection of an immune reaction following a COVID-19 vaccination.

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Lab Automation Software
EURORealTime Analysis

The EURORealTime Analysis software provides simplified processing and fully automated evaluation of EURORealTime test systems. EURORealTime Analysis enables the entry of samples and their allocation to the respective tests. In order to support the subsequent pipetting, the software automatically calculates pipetting schemes and MasterMix preparations based on the input data.

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Lab Automation Software
EUROLineScan

The EUROLineScan software performs fully automated, quantitative evaluation of EUROIMMUN blot strips, and administration and electronic archiving of the individual data. The incubated strips or slides are scanned onto a work protocol using a flatbed scanner (EUROBlotScanner), or by means of the integrated camera system (EUROBlotOne) while still in the incubation tray. EUROLineScan automatically recognizes the position of the strips, identifies the bands and measures their intensity.

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Lab Automation Software
EUROPicture

The EUROPicture program is designed for image acquisition, visualization and administration of fluorescence images in in vitro diagnostics. EUROPicture enables images to be saved for archiving, result reports and later viewing. In addition, images can be sent to EUROIMMUN AG for support in interpretation of fluorescence patterns.

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Fully Automated ELISA Workstation
EUROLabWorkstation ELISA

The EUROLabWorkstation ELISA is a fully automated complete solution for processing ELISA kits in laboratories with high sample throughput. The system focuses on efficiency and flexibility, in order to accommodate the ever increasing sample numbers and changing dynamics in the routine laboratory. Ten washable needles, complementary accessories and a separate robotic arm for handling the microplates enable unparalleled sample throughput. State-of-the-art, intuitive software guides the user graphically through all work steps.

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SARS-CoV-2 IGRA
SARS-CoV-2 IGRA

The SARS-CoV-2 IGRA is an interferon-gamma release assay (IGRA) for the quantitative determination of the IFN-γ release of SARS-CoV-2-specific T cells.

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SARS-CoV-2 sVNT Test
SARS-CoV-2-NeutraLISA

The SARS-CoV-2-NeutraLISA is a surrogate virus neutralization test (sVNT) for the semi-quantitative detection of neutralizing antibodies inhibiting the binding of SARS-CoV-2 S1/RBD to ACE2 receptors of the host cells. It supports the evaluation of the immune response after SARS-CoV-2 infection or vaccination using S1/RBD-based vaccines.

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Nucleic Acid Extractor
Pre-NAT II

The Pre-NAT II allows fully automated high-throughput sample preparation for molecular genetic diagnostics, consisting of nucleic acid extraction and subsequent pipetting of the PCRs. In this way, up to 96 primary samples from various source materials are prepared efficiently, safely and without any manual intermediate steps for subsequent PCR-based tests, e.g. EUROArray and EURORealTime.

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Immunoassay Analyzer
EUROBlotMaster

The EUROBlotMaster and the EUROBlotMaster 44 are compact tabletop devices for processing EUROIMMUN blot strips (EUROLINE, EUROLINE-WB, Westernblot). Following the software-guided loading of reagents, blot strips and samples, the devices perform all incubation and wash steps of the work protocol, as well as the dispensing of buffers, conjugates and substrate and stop solutions. Different conjugates and tests for autoimmune, infection and allergy diagnostics can be combined in one run. EUROBlotMaster devices have an integrated display with a membrane keyboard and do not require an additional PC. They are convenient and simple to operate using six keys and require minimal daily maintenance of five minutes at most.

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ELISA Processor
EUROIMMUN Analyzer I-2P

EUROIMMUN Analyzer I-2P enables a quick and simple, but also a secure routine operation, owing to the automatic recognition and allocation of reagents and the import of QC data via Data Matrix codes. Designed for low to medium sample volumes, a further quality feature of EUROIMMUN Analyzer I-2P is the optionally available climate control unit, which ensures constant incubation conditions - regardless of fluctuating or excessively high laboratory temperatures.

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Blood Collection Set
Blood Collection Set

Euroimmun’s Blood Collection Set for COVID-19 diagnostics using dried capillary blood enables convenient sample collection for the company’s CE-marked ELISAs for the detection of anti-SARS-CoV-2 antibodies (IgG). The use of dried blood spots (DBS) as sample material reduces the blood collection to a quick prick into the fingertip, sparing patients the burdensome and stressful collection of venous blood. The blood spot is brought onto the blood collection card and after drying, it can be sent to the laboratory immediately. All the required materials are included in the EUROIMMUN Blood Collection Set, including alcohol pad, lancet, blood collection card and plasters, while the blood collection cards can also be purchased separately.

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Anti-SARS-CoV-2 ELISA IgA
Anti-SARS-CoV-2 ELISA IgA

Anti-SARS-CoV-2 ELISA IgA is a sensitive ELISA test for the determination of IgA antibodies against SARS-CoV-2 with optimized specificity due to the use of sample buffer PLUS. It makes use of the spike protein domain S1 as the antigen for monitoring the immune response after positive direct pathogen detection, and makes fully automated processing and evaluation possible.

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Anti-SARS-CoV-2 NCP ELISA (IgM)
Anti-SARS-CoV-2 NCP ELISA (IgM)

Anti-SARS-CoV-2 NCP ELISA (IgM) is intended for the sensitive detection of IgM against SARS-CoV-2 using the nucleocapsid protein, the antigen with the strongest immune dominance in the coronavirus family. It offers optimized specificity of the ELISA due to the use of a modified nucleocapsid protein (NCP) that only contains diagnostically relevant epitopes, and allows for fully automated processing and evaluation.

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Anti-SARS-CoV-2 NCP ELISA (IgG)
Anti-SARS-CoV-2 NCP ELISA (IgG)

Anti-SARS-CoV-2 NCP ELISA (IgG) is intended for the sensitive detection of IgG against SARS-CoV-2 using the nucleocapsid protein, the antigen with the strongest immune dominance in the coronavirus family. The fully automatable test offers optimized specificity of the ELISA due to the use of a modified nucleocapsid protein (NCP) that only contains diagnostically relevant epitopes and has been validated for serum, plasma and dried capillary blood as sample material.

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Anti-SARS-CoV-2 ELISA (IgG)
Anti-SARS-CoV-2 QuantiVac ELISA (IgG)

The Anti-SARS-CoV-2 QuantiVac ELISA (IgG) is a quantitative ELISA for the determination of concentration of IgG antibodies against the S1 antigen (incl. RBD) of SARS-CoV-2 in a broad linear range (using a 6-point calibration curve). Validated for serum, plasma and dried capillary blood as sample material, the test enables issuing of results in standardized units and demonstrates very good agreement of results in comparison with different neutralization tests.

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Anti-SARS-CoV-2 ELISA IgG
Anti-SARS-CoV-2 ELISA IgG

The Anti-SARS-CoV-2 ELISA IgG is intended for the specific detection of IgG against SARS-CoV-2 using the S1 domain of the spike protein, including the immunologically relevant receptor binding domain (RBD). Its excellent performance and good correlation with neutralization tests has been confirmed in external studies, and the fully automatable test has been validated for serum, plasma and dried capillary blood as the sample material.

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SARS-CoV-2 Antigen ELISA
SARS-CoV-2 Antigen ELISA

SARS-CoV-2 Antigen ELISA is a laboratory diagnostic test for the direct detection of SARS-CoV-2 by semi-quantitative determination of the virus-specific nucleocapsid protein in swab samples from the upper respiratory tract. Designed to support acute diagnostics, especially during a COVID-19 outbreak, the test is based on the established ELISA method, making it suitable for every diagnostic laboratory and is fully automatable.

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SARS-CoV-2/Influenza A/B PCR Test
EURORealTime SARS-CoV-2/Influenza A/B

EURORealTime SARS-CoV-2/Influenza A/B is a reliable PCR test for the specific detection of SARS-CoV-2, including the variants alpha (B.1.1.7 lineage), beta (B.1.351 lineage), gamma (P.1 lineage), delta (B1.617.2 lineage), lambda (C.37 lineage), mu (B.1.621 lineage) and omicron (B.1.1.529 lineage), as well as of influenza virus types A and B. It enables quick and simple pathogen detection by means of reverse transcription and real-time PCR in one step, and is intended for differential diagnostic clarification of symptoms that can be associated with COVID-19 as well as influenza.

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SARS-CoV-2 PCR Test
EURORealTime SARS-CoV-2

EURORealTime SARS-CoV-2 is a PCR test for the specific detection of SARS-CoV-2, including the variants alpha (B.1.1.7 lineage), beta (B.1.351 lineage), gamma (P.1 lineage), delta (B1.617.2 lineage), lambda (C.37 lineage), mu (B.1.621 lineage) and omicron (B.1.1.529 lineage). The test enables quick and simple pathogen detection by means of reverse transcription and real-time PCR in one step, and has high sensitivity due to simultaneous detection of two SARS-CoV-2 target sequences.

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COVID-19 PCR and ELISAs
COVID-19 PCR and ELISAs

EUROIMMUN’s portfolio for COVID-19 diagnostics includes the EURORealTime SARS-CoV-2 for sensitive direct virus detection, as well as ELISAs based on spike protein domain S1 (IgG, IgA) or modified nucleocapsid protein (NCP, IgG). The IgG ELISAs demonstrate specificities of 99.6% and 99.8% and sensitivities of 94.4% and 94.6%, respectively. The antibody detection can also be performed using dried blood spots taken with the Blood Collection Set. The ELISAs can be processed fully automatically, for example on the EUROLabWorkstation ELISA. All the tests are CE marked.

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Aspergillus Antigen ELISA
Aspergillus Antigen ELISA

The Aspergillus Antigen ELISA provides quantitative in vitro determination of Aspergillus spp. to support the diagnosis of invasive aspergillosis. The test is based on a monoclonal antibody for the detection of Aspergillus-specific galactomannoprotein, which is produced during active fungal growth. The procedure is performed on patient serum or bronchoalveolar lavage fluid and can be semi-automated. In a published study the test yielded comparable sensitivity and specificity to another commercially available ELISA (J. Clin. Microbiol, Apr 2019).

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Immunofluorescence Analyzer (IFA)
EUROLabWorkstation IFA

The EUROLabWorkstation IFA provides fully automated processing of indirect immunofluorescence assays at a capacity of up to 750 reaction fields per run. It is the highest throughput system on the market, processing more than 200 tests per hour. The instrument offers flexible loading of samples and reagents and incorporates automatic mounting of slides. Its 10 washable needles provide economical and precise pipetting. The automatic identification of patient samples, reagents, slides and dilution plates ensures complete traceability. The system is easy to operate using the intuitive touch-screen user interface.

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Microscope
EUROPattern Microscope Live

The EUROPattern Microscope Live is a compact device for on-screen microscopy and fully automated acquisition of fluorescence images. The novel automatic laser focusing enables fast processing in less than two seconds per image. The microscope includes an integrated controlled LED and fluorescence standard for constant illumination. The middleware EUROLabOffice 4.0 generates patient reports and archives all data and images. The software communicates bidirectionally with the LIS, ensuring a smooth laboratory routine.

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ELISA Analyzer
EUROIMMUN Analyzer I

The EUROIMMUN Analyzer I provides fully automated ELISA processing for medium to high sample volume with minimal manual input. More than 800 validated EUROIMMUN parameters for autoimmune, infection and allergy diagnostics can be processed on the open system, and up to 70 tests results are generated per hour. Automated barcode identification of patient samples and reagents ensures security and traceability. The user-friendly graphical interface and low-maintenance hardware provide convenient and secure operation.

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Microscope
EUROStar III Plus / cLED

The EUROStar III Plus/cLED fluorescence microscope features the EUROStar Bluelight system with LED having a life expectancy of 50,000 hours and light intensity maintained at a constant level by electronic regulation. Switching between the camera and the eyepieces is unnecessary due to the convenient 50/50 beam splitter, while its halogen transmitted-light source makes it suited for brightfield, darkfield and, optionally, for phase contrast microscopy.

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25-OH Vitamin D ELISA
25-OH Vitamin D ELISA

The EUROIMMUN 25-OH Vitamin D ELISA provides optimized and reliable detection of total 25-OH vitamin D3 and D2. The quick and simple test can be performed in less than three hours and is automatable on open ELISA processors. It shows an excellent correlation with reference methods and good agreement with target values of reference materials.

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Calprotectin ELISA
Calprotectin ELISA

The EUROIMMUN Calprotectin ELISA is a non-invasive stool test for the differentiation of chronic inflammatory bowel diseases, such as Crohn’s disease and ulcerative colitis, from functional gut disorders, such as irritable bowel syndrome. It aids selection of patients who should undergo endoscopy and is useful for monitoring the disease activity and predicting relapses.

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Dermatomycosis Assay
EUROArray Dermatomycosis

The EUROArray Dermatomycosis provides direct detection and differentiation of the most important dermatomycosis pathogens in one test. The assay simultaneously detects 50 dermatophyte species, and provides species identification for 23 of these as well as for six yeasts and moulds. The fast and sensitive detection yields results within 24 hours. The PCR-based test is simple to perform and includes fully automated evaluation and interpretation of results.

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Microarray Scanner
EUROArrayScan-System

The EUROArrayScan-System is designed for fully automated evaluation of EUROIMMUN microarrays and delivers standardized, fast and reliable results. After the incubated slides have been placed into the microarray scanner, the scanning procedure is initiated by just a mouse click and results for a EUROArray slide (up to five samples) are obtained in less than 20 seconds.

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Anti-Mayaro Virus ELISA (IgG, IgM)
Anti-Mayaro Virus ELISA (IgG, IgM)

The Anti-Mayaro Virus ELISA (IgM, IgG) provides highly sensitive detection of antibodies against Mayaro virus (MAYV) in patient serum samples, supporting diagnosis of acute as well as past MAYV infections. Specific IgM antibodies can be detected soon after symptom onset, while specific IgG antibodies may persist for many years. The ELISA is especially useful for differential diagnostics of arboviral infectious diseases with similar clinical symptoms, e.g. Zika, dengue and Oropouche fever.

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Multiparameter Test
EUROLINE DPA-Dx Pollen Southern Europe 1

The EUROLINE DPA-Dx Pollen Southern Europe 1 detects and differentiates specific IgE antibodies against inhalation allergens that commonly occur in Southern Europe. It identifies the allergy-causing proteins, distinguishing primary sensitizations from cross reactions, and aids therapy decisions. The test is based on a unique combination of species-specific marker molecules, cross-reactive components and whole extracts encompassing tree, grass and weed pollens as well as the fungus Alternaria alternata.

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Immunoassay Analyzer
RA Analyzer 10

The RA Analyzer 10 is a compact random access instrument, which provides fully automated processing of chemiluminescence immunoassays (ChLIA) for autoimmune and infection diagnostics. The device allows continuous loading, also as part of a laboratory track system, ensuring that every sample is processed with minimal effort as a single determination. Barcode identification and RFID technology ensure convenient and secure operation. The preferential processing of emergency samples (STAT) gives laboratories unparalleled flexibility in their laboratory routine.

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Immunoassay Analyzer
EUROBlotOne

The EUROBlotOne is a fully automated system for the processing of immunoblot tests – from sample -identification to the final result – for autoimmune, infection and allergy diagnostics with minimal manual effort. It offers precision and reproducibility from the first incubation step to the recording of images of the incubated immunoblot strips and allows for combination of different tests in one run.

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IFT Slide Washer
MERGITE!

The MERGITE! device provides fully automated washing of incubated immunofluorescence slides, increasing the efficiency and reproducibility of analyses. In the high-throughput procedure up to 50 substrates are washed in parallel. The gentle, meticulous washing procedure ensures brilliant fluorescence signals. Cross contamination is prevented by separate washing of each field. The standardized, predefined wash programs ensure a consistent washing quality and high reproducibility. The compact tabletop device includes an integrated touch screen for convenient operation.

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Immunoanalyzer
Sprinter XL

The Sprinter XL analyzer allows for fully-automated processing of immunofluorescence tests and ELISA on one device, along with flexibility for making individual adjustments as per different laboratory requirements and tests. Other key features include four washable pipetting needles, two independent robot arms, optimal workflow calculation, user-friendly graphical interface and low-maintenance hardware.

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DNA Microarray Test
EUROArray STI

The EUROArray STI provides parallel direct detection of up to 11 sexually transmitted pathogens in one reaction. It is particularly suitable for detecting pathogens that are difficult or impossible to cultivate. The combined detection is useful for clarifying ambiguous clinical findings, identifying asymptomatic infections, and identifying multiple infections with different sexually transmitted pathogens. Early diagnosis of STI can help to prevent infertility and miscarriages. The procedure is easy to perform and includes fully automated evaluation and interpretation of results.

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ELISA Processing System
EUROLabWorkstation ELISA

The EUROLabWorkstation ELISA provides fully automated processing of EUROIMMUN ELISA tests at a capacity of up to 15 plates per run. It is the highest throughput system on the market, processing more than 200 tests per hour. The instrument offers flexible loading of samples, reagents and dilution plates. Its 10 washable needles provide economical and precise pipetting. The automatic identification of patient samples, reagents, and dilution and ELISA plates ensures complete traceability. The system is easy to operate using the intuitive touch-screen user interface.

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ELISA Test
Anti-Chikungunya Virus ELISA

The Anti-Chikungunya Virus ELISA (IgM, IgG) enables detection of specific antibodies against chikungunya virus for serological confirmation of acute or past infections. It is especially useful for differential diagnostics of arboviral infectious diseases with similar clinical symptoms, e.g. Zika and dengue fever.

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Microscope
EUROPattern

The EUROPattern system provides fully automated immunofluorescence microscopy and state-of-the-art diagnostics at the computer screen. It includes pattern recognition for ANA (based on ICAP) and ANCA, as well as positive/negative classification for Crithidiae luciliae, antigen-expressing cells and antigen dots. Images are processed at high speed (13 seconds per image) and results are consolidated into one report per patient. All fluorescence images and reports are digitally archived. The system communicates bi-directionally with the LIS, streamlining work processes in the laboratory.

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Microarray Test
EUROArray HLA-B*57:01

The EUROarray HLA-B*57:01 analysis is fast and simple, and does not require in-depth molecular biology knowledge. The test identifies the presence of the HLA-B*57:01 allele, and helps prevent hypersensitivity and adverse reactions to abacavir-containing drugs in HIV patients.

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HPV DNA Microarray
HPV EUROArray

The EUROArray HPV provides detection of all 30 HPV subtypes in one test, distinguishing between 18 high-risk subtypes that trigger cervical cancer and 12 low-risk subtypes. The test meets the international criteria for HPV screening in cervical cancer prevention defined by Meijer et al. The PCR-based detection allows in particular the identification of persistent or multiple infections with high-risk subtypes, which are associated with an increased tumour risk. The procedure is easy to perform and includes fully automated evaluation and interpretation of results.

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Autoantibody Biomarker
Anti-PLA2R ELISA (IgG)

The Anti-PLA2R ELISA and the Anti-PLA2R ChLIA provide quantitative in vitro determination of antibodies against phospholipase A2 receptors. Anti-PLA2R and the supplementary marker anti-THSD7A can be detected in parallel using indirect immunofluorescence tests based on antigen-expressing cells. Anti-PLA2R and anti-THS7DA antibodies are highly specific markers for primary membranous nephropathy. Their analysis supports differential diagnosis, disease monitoring, and risk assessment.

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